McCabe M A, Getson P, Brasseux C, Johnson D L
Cancer Pract. 1995 Jan-Feb;3(1):47-53.
A growing literature documents the deleterious effects of radiation therapy in children treated for malignant brain tumors. However, the clinical relevance of previous research has been limited by reliance on global IQ and achievement test scores. The present study of a sample of long-term survivors of medulloblastoma examined their cognitive and socioemotional functioning in depth with standardized psychologic measures. Participants' levels of intellectual functioning ranged from moderately mentally retarded to low average, with marked scatter across individual skills. Thirty-nine percent of participants had formal learning disabilities, with achievement substantially below their learning potential. In terms of specific areas of deficit, almost one half the patients tested (47%) showed considerable impairment in perceptual-motor coordination, fine-motor dexterity, attention and concentration, sequencing, and memory, particularly visual memory. More than one half of the sample (54%) was also described as displaying severe impairment in terms of maladaptive behaviors. Results are discussed in terms of the implications for special education, everyday skills, and psychosocial program development.
越来越多的文献记录了放射治疗对接受恶性脑肿瘤治疗的儿童的有害影响。然而,先前研究的临床相关性受到对整体智商和成绩测试分数的依赖的限制。本研究对髓母细胞瘤长期幸存者样本进行了深入研究,采用标准化心理测量方法考察了他们的认知和社会情感功能。参与者的智力功能水平从中度智力迟钝到低平均水平不等,个体技能之间存在明显差异。39%的参与者有正式的学习障碍,成绩远低于他们的学习潜力。在特定的缺陷领域,近一半接受测试的患者(47%)在感知运动协调、精细运动灵活性、注意力和专注力、排序和记忆,尤其是视觉记忆方面表现出相当大的损伤。超过一半的样本(54%)也被描述为在适应不良行为方面表现出严重损伤。本文将根据这些结果对特殊教育、日常技能和心理社会项目发展的影响进行讨论。