Bull World Health Organ. 1995;73(1):15-20.
Hepatitis A virus infection is a significant cause of morbidity in many parts of the world, and hepatitis A vaccines will be important tools for its prevention and control. This Memorandum reviews the basic features of the disease and its epidemiology, and considers the measures which are available for control and prevention, including hepatitis A vaccine. The use of this vaccine should be adapted to specific epidemiological circumstances existing within a geographical region, with special attention to the cost-effectiveness of immunization programmes.
甲型肝炎病毒感染是世界许多地区发病的重要原因,甲型肝炎疫苗将成为预防和控制该疾病的重要工具。本备忘录回顾了该疾病的基本特征及其流行病学情况,并考虑了可用于控制和预防的措施,包括甲型肝炎疫苗。该疫苗的使用应适应某一地理区域内现有的特定流行病学情况,尤其要关注免疫规划的成本效益。