Rodríguez Rodríguez E M, Sanz Alaejos M, Díaz Romero C
Department of Analytical Chemistry, Food Science and Toxicology, University of La Laguna, Spain.
Clin Chim Acta. 1994 Nov;231(1):39-46. doi: 10.1016/0009-8981(94)90252-6.
Urinary selenium (Se) concentrations (micrograms Se/l and microgram Se/g creatinine) have been determined in heroin abusers and in healthy controls. Heroin abusers showed significantly (P < 0.050) lower urinary Se concentrations (microgram Se/l and microgram Se/g creatinine) than healthy controls. The decrease of the urinary Se concentration (microgram Se/g creatinine) observed with the increase in age of heroin abusers may be due to the higher exposure to heroin with increased age. No significant differences (P > 0.100) of urinary Se concentrations (both as microgram Se/l and microgram Se/g creatinine) are observed between heroin abusers during methadone treatment and heroin abusers who have stopped taking the drug, with respect to healthy controls.
已测定海洛因滥用者和健康对照者的尿硒（Se）浓度（微克硒/升和微克硒/克肌酐）。海洛因滥用者的尿硒浓度（微克硒/升和微克硒/克肌酐）显著低于健康对照者（P < 0.050）。随着海洛因滥用者年龄增长，观察到尿硒浓度（微克硒/克肌酐）下降，这可能是由于随着年龄增长，海洛因暴露量增加。与健康对照者相比，接受美沙酮治疗的海洛因滥用者和已停止服药的海洛因滥用者之间，尿硒浓度（微克硒/升和微克硒/克肌酐）均未观察到显著差异（P > 0.100）。
