Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1).
作者信息
Hahn M, Fislage R, Pingoud A
机构信息
Institut für Biochemie, Justus-Liebig-Universität, Giessen, Germany.
出版信息
Hum Genet. 1995 Apr;95(4):471-2. doi: 10.1007/BF00208983.
PMID:7705850
Abstract
DyeDeoxy terminator cycle sequencing of allele-specific polymerase chain reaction products has shown that there is a highly polymorphic d(AAAAT) pentanucleotide repeat within the first intron of the human p53 gene. This provides a genetic marker for tumor suppressor p53 gene alterations.
摘要
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