Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1). - Suppr | 超能文献

Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1).

作者信息

Hahn M, Fislage R, Pingoud A

机构信息

Institut für Biochemie, Justus-Liebig-Universität, Giessen, Germany.

出版信息

Hum Genet. 1995 Apr;95(4):471-2. doi: 10.1007/BF00208983.

DOI:10.1007/BF00208983

Abstract

DyeDeoxy terminator cycle sequencing of allele-specific polymerase chain reaction products has shown that there is a highly polymorphic d(AAAAT) pentanucleotide repeat within the first intron of the human p53 gene. This provides a genetic marker for tumor suppressor p53 gene alterations.

摘要

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