Bulyalert D
Department of Internal Medicine, Chiang Mai University Faculty of Medicine, Thailand.
Int J Biomed Comput. 1994 Oct;37(2):181-7. doi: 10.1016/0020-7101(94)90140-6.
An interactive simulation of neuronal synaptic potential is presented. The set-up comprises of two synaptic terminals and one postsynaptic membrane from which the intracellular potential is recorded. Certain parameters are interactively changeable by the user. For example, each synaptic terminal may cause changes in the membrane conductance to sodium, potassium, or chloride ions, or some combinations of them. One synaptic terminal may be turned on/off to allow study of the spatio-temporal summation of postsynaptic potentials with adjustable delay. The postsynaptic membrane may also be set at various values in order to study the effects of membrane potentials on the direction and magnitude of postsynaptic potentials. This simulation has been used with some success as an aid for teaching cellular neurophysiology.
本文展示了一种神经元突触电位的交互式模拟。该装置由两个突触终末和一个记录细胞内电位的突触后膜组成。某些参数可由用户交互式更改。例如，每个突触终末可引起钠、钾或氯离子或它们的某些组合的膜电导变化。一个突触终末可以打开/关闭，以研究具有可调延迟的突触后电位的时空总和。突触后膜也可以设置为各种值，以研究膜电位对突触后电位的方向和幅度的影响。该模拟已成功用于辅助细胞神经生理学教学。
