Clerehugh V, Worthington H V, Lennon M A, Chandler R
Unit of Periodontics, University Dental Hospital of Manchester, UK.
J Clin Periodontol. 1995 Jan;22(1):15-21. doi: 10.1111/j.1600-051x.1995.tb01766.x.
The aims of this study were (1) to monitor the progression and patterns of progression of loss of attachment > or = 1 mm on a site basis over a 5-year period in adolescents, and (2) to relate the presence of oral deposits and inflammation to the subsequent development and progression of loss of attachment on a site basis. 167 subjects were examined at ages 14, 16 and 19 years. Loss of attachment > or = 1 mm, plaque, subgingival calculus, gingival bleeding and gingival colour change were assessed on the mesio-buccal sites of the 1st molars, 1st premolars and central incisors. Each site was treated separately in the analysis to avoid the problem of within-subject site dependence. Sites were classed as progressing, non-progressing or fluctuating according to the probing attachment level measurements at each of the 3 examinations. During the 5 years of this study, a total of 542 sites in 128 subjects progressed; 1136 sites in 162 subjects did not progress; 43 sites in 30 subjects had fluctuating attachment level measurements. Sites which subsequently progressed had significantly more plaque, subgingival calculus and gingival inflammation than non-progressing sites at the baseline examination and throughout the study (p < 0.001). Between 55-57% of the maxillary 1st molars and 46-49% of the mandibular incisors progressed. In contrast, there was no progression of loss of attachment on over 80% of the maxillary central incisors and mandibular 1st premolars.
（1）在5年期间，以位点为基础监测青少年中附着丧失≥1mm的进展情况和进展模式；（2）以位点为基础，将口腔沉积物和炎症的存在与随后附着丧失的发生和进展联系起来。在14岁、16岁和19岁时对167名受试者进行了检查。在第一磨牙、第一前磨牙和中切牙的近中颊侧位点评估附着丧失≥1mm、菌斑、龈下牙石、牙龈出血和牙龈颜色变化。在分析中对每个位点分别进行处理，以避免受试者内位点依赖性问题。根据3次检查中每次的探诊附着水平测量结果，将位点分为进展型、非进展型或波动型。在本研究的5年期间，128名受试者中的542个位点进展；162名受试者中的1136个位点未进展；30名受试者中的43个位点附着水平测量结果波动。在基线检查时及整个研究过程中，随后进展的位点比未进展的位点有明显更多的菌斑、龈下牙石和牙龈炎症（p<0.001）。上颌第一磨牙的55 - 57%和下颌切牙的46 - 49%发生进展。相比之下，超过80%的上颌中切牙和下颌第一前磨牙没有附着丧失的进展。
