Tataranni P A, Larson D E, Ravussin E
Clinical Diabetes and Nutrition Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona.
J Am Coll Nutr. 1994 Dec;13(6):569-74. doi: 10.1080/07315724.1994.10718449.
Upper body obesity seems to be associated with a better prognosis for weight loss than does lower body obesity. However, the impact of body fat distribution on energy metabolism is not clear.
One hundred fifteen non-diabetic obese Caucasians (64 males and 51 females) and 108 Caucasian lean controls (82 males and 26 females) were studied.
Body composition was assessed by hydrodensitometry and body fat distribution was estimated by the waist-to-thigh circumference ratio (W/T). Values of 24-hour energy expenditure (24h-EE), basal metabolic rate (BMR), sleeping metabolic rate (SMR) and respiratory quotient (RQ) were measured in a respiration chamber.
BMR, adjusted for differences in fat-free mass, fat mass, age and sex, correlated with W/T in obese males (r = 0.40; p < 0.01), but not in obese females. Obese male subjects with upper body obesity had BMR significantly higher than those with lower body obesity (2189 +/- 268 vs 1974 +/- 141 kcal/day; p < 0.01), independently of differences in fat-free mass, fat mass and age. No correlations were found between W/T and adjusted 24h-EE, SMR or RQ in all examined groups.
These findings indicate that in obese males, upper body obesity is associated with increased metabolic rate, possibly related to higher levels of lipid turnover in visceral fat.
与下半身肥胖相比，上半身肥胖似乎与更好的减肥预后相关。然而，体脂分布对能量代谢的影响尚不清楚。
研究了115名非糖尿病肥胖白种人（64名男性和51名女性）和108名白种人瘦对照组（82名男性和26名女性）。
通过水下密度测定法评估身体成分，并通过腰臀围比（W/T）估计体脂分布。在呼吸室内测量24小时能量消耗（24h-EE）、基础代谢率（BMR）、睡眠代谢率（SMR）和呼吸商（RQ）的值。
在调整了去脂体重、脂肪量、年龄和性别的差异后，BMR与肥胖男性的W/T相关（r = 0.40；p < 0.01），但与肥胖女性无关。上半身肥胖的肥胖男性受试者的BMR显著高于下半身肥胖的受试者（2189 +/- 268 vs 1974 +/- 141千卡/天；p < 0.01），与去脂体重、脂肪量和年龄的差异无关。在所有检查组中，未发现W/T与调整后的24h-EE、SMR或RQ之间存在相关性。
这些发现表明，在肥胖男性中，上半身肥胖与代谢率增加有关，可能与内脏脂肪中较高的脂质周转率有关。
