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喉软骨肉瘤

Chondrosarcoma of the larynx.

作者信息

Koka V N, Veber F, Haguet J F, Rachinel O, Freche C, Liguory-Brunaud M D

机构信息

Department of Otolaryngology and Head and Neck Surgery, American Hospital of Paris, Neuilly, France.

出版信息

J Laryngol Otol. 1995 Feb;109(2):168-70. doi: 10.1017/s0022215100129597.

Abstract

A case of a low grade chondrosarcoma of the cricoid cartilage which had been diagnosed initially as a chondroma is presented. The tumour recurred twice after limited surgical resections. Total laryngectomy was inevitable due to near total involvement of the cricoid cartilage and subsequent histological examination revealed a low grade chondrosarcoma. We have discussed in brief, the diagnosis and treatment of chondrosarcomas of the larynx and support the view of conservative surgical management for low grade tumours as they are slow growing and metastases are infrequent. A total laryngectomy may be reserved for salvage or primarily when more than half of the cricoid cartilage needs to be resected. Histological grading reveals the biological behaviour of the tumour and CT scans help in planning the surgery. A regular follow-up is necessary for early detection of recurrences and metastases.

摘要

本文报告一例环状软骨低度软骨肉瘤病例,该病例最初被诊断为软骨瘤。在进行有限的手术切除后,肿瘤复发了两次。由于环状软骨几乎完全受累,全喉切除术不可避免,随后的组织学检查显示为低度软骨肉瘤。我们简要讨论了喉软骨肉瘤的诊断和治疗,并支持对低度肿瘤采取保守手术治疗的观点,因为它们生长缓慢且转移罕见。全喉切除术可留作挽救性手术,或主要在需要切除超过一半环状软骨时进行。组织学分级揭示肿瘤的生物学行为,CT扫描有助于手术规划。定期随访对于早期发现复发和转移很有必要。

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