A组呼吸道合胞病毒的进化：附着蛋白中氨基酸变化逐渐积累的证据。
Evolution of subgroup A respiratory syncytial virus: evidence for progressive accumulation of amino acid changes in the attachment protein.
作者信息
Cane P A, Pringle C R
机构信息
Department of Biological Sciences, University of Warwick Coventry, United Kingdom.
出版信息
J Virol. 1995 May;69(5):2918-25. doi: 10.1128/JVI.69.5.2918-2925.1995.
Abstract
The variability of the attachment (G) proteins of 48 subgroup A isolates of respiratory syncytial virus (RSV) isolated over 38 years has been examined. Nucleotide sequences of two variable regions of the G protein genes were determined following amplification by PCR. The isolates showed temporal rather than geographical clustering, and there was evidence for progressive accumulation of amino acid changes at an average rate of approximately 0.25% per year estimated over the entire protein. The cocirculation of lineages of RSV at present appears to be the result of a process of evolution and survival of particular genotypes and the extinction of others. Analysis of reactivity of the isolates with monoclonal antibodies showed that their antigenic profiles closely paralleled their relatedness by nucleotide sequence, suggesting that antigenic drift due to immune selection may be occurring.
摘要
对38年间分离出的48株呼吸道合胞病毒（RSV）A亚组毒株的附着（G）蛋白变异性进行了研究。通过聚合酶链反应（PCR）扩增后，测定了G蛋白基因两个可变区的核苷酸序列。这些毒株呈现出时间上的聚类而非地理上的聚类，并且有证据表明，在整个蛋白质上估计氨基酸变化以每年约0.25%的平均速率进行渐进积累。目前RSV谱系的共同流行似乎是特定基因型进化和存活以及其他基因型灭绝过程的结果。对这些毒株与单克隆抗体反应性的分析表明，它们的抗原谱与其核苷酸序列的相关性密切平行，这表明可能正在发生由免疫选择导致的抗原漂移。
相似文献
1
Evolution of subgroup A respiratory syncytial virus: evidence for progressive accumulation of amino acid changes in the attachment protein.A组呼吸道合胞病毒的进化：附着蛋白中氨基酸变化逐渐积累的证据。
J Virol. 1995 May;69(5):2918-25. doi: 10.1128/JVI.69.5.2918-2925.1995.
2
Evolutionary pattern of human respiratory syncytial virus (subgroup A): cocirculating lineages and correlation of genetic and antigenic changes in the G glycoprotein.人类呼吸道合胞病毒（A亚组）的进化模式：共循环谱系以及G糖蛋白中基因和抗原变化的相关性
J Virol. 1994 Sep;68(9):5448-59. doi: 10.1128/JVI.68.9.5448-5459.1994.
3
Antigenic structure, evolution and immunobiology of human respiratory syncytial virus attachment (G) protein.人呼吸道合胞病毒附着（G）蛋白的抗原结构、进化及免疫生物学
J Gen Virol. 1997 Oct;78 ( Pt 10):2411-8. doi: 10.1099/0022-1317-78-10-2411.
4
Sequence conservation in the attachment glycoprotein and antigenic diversity among bovine respiratory syncytial virus isolates.牛呼吸道合胞病毒分离株中附着糖蛋白的序列保守性和抗原多样性。
Vet Microbiol. 1997 Mar;54(3-4):201-21. doi: 10.1016/s0378-1135(96)01288-6.
5
Genetic variability of respiratory syncytial virus subgroup a strain in 15 successive epidemics in one city.一个城市连续15次流行中呼吸道合胞病毒A亚组毒株的基因变异性
J Med Virol. 2001 Jul;64(3):374-80. doi: 10.1002/jmv.1061.
6
Conservation of the respiratory syncytial virus SH gene.呼吸道合胞病毒SH基因的保守性。
J Infect Dis. 2000 Oct;182(4):1228-33. doi: 10.1086/315829. Epub 2000 Sep 6.
7
Genetic diversity of the attachment protein of subgroup B respiratory syncytial viruses.B 亚群呼吸道合胞病毒附着蛋白的遗传多样性
J Virol. 1991 Oct;65(10):5425-34. doi: 10.1128/JVI.65.10.5425-5434.1991.
8
Antigenic analysis of chimeric and truncated G proteins of respiratory syncytial virus.呼吸道合胞病毒嵌合和截短G蛋白的抗原分析
Virology. 1995 May 10;209(1):70-9. doi: 10.1006/viro.1995.1231.
9
Analysis of respiratory syncytial virus strain variation in successive epidemics in one city.一个城市连续疫情中呼吸道合胞病毒毒株变异分析
J Clin Microbiol. 1994 Jan;32(1):1-4. doi: 10.1128/jcm.32.1.1-4.1994.
10
Analysis of the ovine respiratory syncytial virus (RSV) G glycoprotein gene defines a subgroup of ungulate RSV.绵羊呼吸道合胞病毒（RSV）G糖蛋白基因分析确定了有蹄类动物RSV的一个亚组。
J Gen Virol. 1993 Dec;74 ( Pt 12):2787-91. doi: 10.1099/0022-1317-74-12-2787.
引用本文的文献
1
A multi-center study on Molecular Epidemiology of Human Respiratory Syncytial Virus from Children with Acute Lower Respiratory Tract Infections in the Mainland of China between 2015 and 2019.2015 年至 2019 年中国大陆儿童急性下呼吸道感染中人呼吸道合胞病毒的分子流行病学多中心研究。
Virol Sin. 2021 Dec;36(6):1475-1483. doi: 10.1007/s12250-021-00430-7. Epub 2021 Aug 16.
2
Respiratory Syncytial Virus G Protein Sequence Variability among Isolates from St. Petersburg, Russia, during the 2013-2014 Epidemic Season.俄罗斯圣彼得堡 2013-2014 流行季呼吸道合胞病毒 G 蛋白分离株序列变异性。
Viruses. 2021 Jan 17;13(1):119. doi: 10.3390/v13010119.
3
Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region.中东和北非（MENA）地区儿童呼吸道合胞病毒（RSV）流行率、基因型分布及季节性的系统评价
Microorganisms. 2020 May 11;8(5):713. doi: 10.3390/microorganisms8050713.
4
The Impact of RSV-Associated Respiratory Disease on Children in Asia.呼吸道合胞病毒相关呼吸道疾病对亚洲儿童的影响。
J Pediatr Infect Dis. 2019 Apr;14(3):79-88. doi: 10.1055/s-0038-1637752. Epub 2018 Apr 11.
5
Summer Outbreak of Severe RSV-B Disease, Minnesota, 2017 Associated with Emergence of a Genetically Distinct Viral Lineage.2017 年明尼苏达州夏季严重呼吸道合胞病毒 B 型疾病暴发与遗传上不同的病毒谱系出现有关。
J Infect Dis. 2020 Jun 29;222(2):288-297. doi: 10.1093/infdis/jiaa075.
6
Respiratory syncytial virus A genotype classification based on systematic intergenotypic and intragenotypic sequence analysis.基于系统的种间和种内序列分析的呼吸道合胞病毒 A 基因型分类。
Sci Rep. 2019 Dec 27;9(1):20097. doi: 10.1038/s41598-019-56552-2.
7
Bornaviruses in naturally infected in Portugal: insights of molecular epidemiology and ecology.葡萄牙自然感染中的博尔纳病毒：分子流行病学与生态学见解
Infect Ecol Epidemiol. 2019 Nov 6;9(1):1685632. doi: 10.1080/20008686.2019.1685632. eCollection 2019.
8
Gradual replacement of all previously circulating respiratory syncytial virus A strain with the novel ON1 genotype in Lanzhou from 2010 to 2017.2010年至2017年期间，兰州地区所有先前流行的呼吸道合胞病毒A株逐渐被新型ON1基因型所取代。
Medicine (Baltimore). 2019 May;98(19):e15542. doi: 10.1097/MD.0000000000015542.
9
Whole genome analysis of local Kenyan and global sequences unravels the epidemiological and molecular evolutionary dynamics of RSV genotype ON1 strains.对肯尼亚当地和全球序列进行的全基因组分析揭示了呼吸道合胞病毒ON1基因型毒株的流行病学和分子进化动态。
Virus Evol. 2018 Sep 24;4(2):vey027. doi: 10.1093/ve/vey027. eCollection 2018 Jul.
10
Evolution of Human Respiratory Syncytial Virus (RSV) over Multiple Seasons in New South Wales, Australia.澳大利亚新南威尔士州多个季节中人类呼吸道合胞病毒（RSV）的演变。
Viruses. 2018 Sep 6;10(9):476. doi: 10.3390/v10090476.
本文引用的文献
1
Sequence variability in the 5' non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity.丙型肝炎病毒5'非编码区的序列变异性：一种新病毒类型的鉴定及序列多样性的限制
J Gen Virol. 1993 Apr;74 ( Pt 4):661-8. doi: 10.1099/0022-1317-74-4-661.
2
Punctuated equilibrium and positive Darwinian evolution in vesicular stomatitis virus.水疱性口炎病毒中的间断平衡与正向达尔文进化
Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10424-8. doi: 10.1073/pnas.90.22.10424.
3
Analysis of respiratory syncytial virus strain variation in successive epidemics in one city.一个城市连续疫情中呼吸道合胞病毒毒株变异分析
J Clin Microbiol. 1994 Jan;32(1):1-4. doi: 10.1128/jcm.32.1.1-4.1994.
4
Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.在人类免疫缺陷病毒1型不同基因谱系中观察到的V3环蛋白序列的突变趋势。
J Virol. 1994 Oct;68(10):6730-44. doi: 10.1128/JVI.68.10.6730-6744.1994.
5
Evolutionary pattern of human respiratory syncytial virus (subgroup A): cocirculating lineages and correlation of genetic and antigenic changes in the G glycoprotein.人类呼吸道合胞病毒（A亚组）的进化模式：共循环谱系以及G糖蛋白中基因和抗原变化的相关性
J Virol. 1994 Sep;68(9):5448-59. doi: 10.1128/JVI.68.9.5448-5459.1994.
6
Evolution of the HA1 domain of human influenza A (H1N1) virus: loss of glycosylation sites and occurrence of herald and conserved strains.
J Gen Virol. 1995 Jan;76 ( Pt 1):205-10. doi: 10.1099/0022-1317-76-1-205.
7
Human parainfluenza virus type 1 evolution combines cocirculation of strains and development of geographically restricted lineages.1型人副流感病毒的进化包括毒株的共同流行以及地理局限谱系的发展。
J Infect Dis. 1994 Feb;169(2):248-52. doi: 10.1093/infdis/169.2.248.
8
Antigenic drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes at key antigenic sites.1968年至1980年流感病毒H3血凝素的抗原漂移：关键抗原位点的多种进化途径和连续氨基酸变化
J Virol. 1983 Oct;48(1):52-60. doi: 10.1128/JVI.48.1.52-60.1983.
9
The antigenicity and evolution of influenza H1 haemagglutinin, from 1950-1957 and 1977-1983: two pathways from one gene.1950年至1957年以及1977年至1983年期间甲型流感病毒H1血凝素的抗原性与进化：源于一个基因的两条路径
Virology. 1986 Jan 30;148(2):275-87. doi: 10.1016/0042-6822(86)90325-9.
10
Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein.人类呼吸道合胞病毒G蛋白基因的核苷酸序列揭示了一种不同寻常的病毒膜蛋白类型。
Proc Natl Acad Sci U S A. 1985 Jun;82(12):4075-9. doi: 10.1073/pnas.82.12.4075.
Zotero 插件