Resnick D K, Jannetta P J, Bissonnette D, Jho H D, Lanzino G
University of Pittsburgh School of Medicine, Department of Neurological Surgery, Presbyterian University Hospital, Pennsylvania.
Neurosurgery. 1995 Jan;36(1):64-8; discussion 68-9. doi: 10.1227/00006123-199501000-00008.
Glossopharyngeal neuralgia is an uncommon cause of facial pain with a relative frequency of 0.2 to 1.3% when compared with trigeminal neuralgia. It is characterized by intermittent, lancinating pain involving the posterior tongue and pharynx, often with radiation to deep ear structures. Since its first description in 1910 by Weisenburg, a variety of destructive procedures have been performed to provide relief in patients whose pain was refractory to medical treatment. These procedures all necessitated the sacrifice of the glossopharyngeal nerve and, in most cases, also involved the destruction of at least part of the vagus nerve as well. In 1977, Laha and Jannetta reported good results in four patients who underwent microvascular decompression of the glossopharyngeal and vagus nerves for glossopharyngeal neuralgia. Since 1971, 40 patients have undergone microvascular decompression of the glossopharyngeal and vagus nerves for treatment of typical glossopharyngeal neuralgia. This procedure provided excellent immediate results (complete or > 95% relief of pain) in 79%, with an additional 10% having a substantial (> 50%) reduction in pain. Long-term follow-up (mean, 48 mo; range, 6-170 mo) reveals excellent results (complete or > 95% reduction in pain without any medication) in 76% of the patients and substantial improvement in an additional 16%. There were two deaths at surgery (5%) both occurring early in the series as the result of hemodynamic lability causing intracranial hemorrhage. Three patients (8%) suffered permanent 9th nerve palsy. (ABSTRACT TRUNCATED AT 250 WORDS)
舌咽神经痛是一种少见的面部疼痛病因,与三叉神经痛相比,其相对发病率为0.2%至1.3%。其特点是间歇性、刀割样疼痛,累及舌后部和咽部,常放射至深部耳部结构。自1910年魏森堡首次描述该病以来,已实施了多种破坏性手术,以缓解药物治疗无效患者的疼痛。这些手术都需要牺牲舌咽神经,而且在大多数情况下,还至少会破坏部分迷走神经。1977年,拉哈和詹内塔报告了4例因舌咽神经痛接受舌咽神经和迷走神经微血管减压术的患者取得了良好效果。自1971年以来,40例患者因典型舌咽神经痛接受了舌咽神经和迷走神经微血管减压术。该手术在79%的患者中取得了极佳的即刻效果(疼痛完全缓解或减轻>95%),另有10%的患者疼痛大幅减轻(>50%)。长期随访(平均48个月;范围6至170个月)显示,76%的患者取得了极佳效果(无需任何药物,疼痛完全缓解或减轻>95%),另有16%的患者有显著改善。手术中有2例死亡(5%),均发生在该系列早期,系血流动力学不稳定导致颅内出血所致。3例患者(8%)出现永久性第9神经麻痹。(摘要截短于250词)