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[肺癌患者血浆中的铜和锌水平]

[Level of copper and zinc in plasma of patients with lung cancer].

作者信息

Bronisz M, Tyrakowska J, Przybylski G, Wojciechowska V

机构信息

Kliniki Ftizjopneumonologii AM w Bydgoszczy.

出版信息

Pol Tyg Lek. 1994;49(18-19):419-20.

PMID:7708569
Abstract

Microelements metabolic disorders, including copper and zinc, constitute an important field of cancer studies. Efforts are undertaken to identify cancer markers. Found changes in plasma copper and zinc levels in patients with lung carcinoma may have clinical implications, and help in the diagnosis despite the fact that there are no reports in the literature confirming specificity of these two elements for lung carcinoma. Plasma copper and zinc levels were determined in blood samples of 94 patients with lung carcinoma with atomic absorption technique. The obtained results were compared with those in 20 healthy blood donors, and were analysed statistically and plotted graphically. Statistically significant differences in patient's plasma vs control group were noted.

摘要

包括铜和锌在内的微量元素代谢紊乱是癌症研究的一个重要领域。人们致力于识别癌症标志物。肺癌患者血浆铜和锌水平的变化可能具有临床意义,并有助于诊断,尽管文献中没有报道证实这两种元素对肺癌的特异性。采用原子吸收技术测定了94例肺癌患者血样中的血浆铜和锌水平。将所得结果与20名健康献血者的结果进行比较,并进行统计学分析和绘制图表。结果发现患者血浆与对照组之间存在统计学显著差异。

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