Clugston P A, Fitzpatrick D G, Kester D A, Foley B, Germann E
Department of Surgery, Vancouver General Hospital, British Columbia, Canada.
Plast Reconstr Surg. 1995 Apr;95(5):824-8.
A study was undertaken to evaluate the current use of autologous blood predonation within 3 weeks of reduction mammaplasty in our institution. A retrospective study of 153 consecutive patients undergoing reduction mammaplasty between April of 1987 and October of 1992 was analyzed. Nine patients were excluded because of inadequate data, leaving 81 patients in the autologous blood predonation study group and 63 patients in the control group. The two groups were similar with regard to age, preintervention hemoglobin levels, technique of reduction mammaplasty, average number of grams excised per side, estimated blood loss, and duration of hospital stay. Those in the study group, despite preoperative iron therapy initiated just prior to the time of autologous blood donation, had significantly lower preoperative hemoglobin levels (p < 0.001). Seventy-two percent of those patients who donated blood preoperatively received all their blood intraoperatively or within 1 day of surgery. Eleven percent received 1 of their 2 units donated, and the remaining 17 percent were not transfused. Despite 83 percent of the study group patients receiving all or some of their predonated blood, their postoperative hemoglobin levels were not significantly different from those of the control group. We concluded that under our current program, autologous blood predonation for reduction mammaplasty is not beneficial to the patient in the immediate perioperative period.
本研究旨在评估我院在缩乳术3周内自体血预存的当前使用情况。对1987年4月至1992年10月期间连续接受缩乳术的153例患者进行回顾性研究分析。9例患者因数据不充分被排除，自体血预存研究组有81例患者，对照组有63例患者。两组在年龄、干预前血红蛋白水平、缩乳术技术、每侧切除的平均克数、估计失血量和住院时间方面相似。研究组患者尽管在自体血捐献前开始进行术前铁剂治疗，但术前血红蛋白水平仍显著较低（p < 0.001）。72%的术前献血患者在术中或术后1天内接受了全部自体血。11%的患者接受了所献2单位血液中的1单位，其余17%未接受输血。尽管研究组83%的患者接受了全部或部分预存血，但他们术后的血红蛋白水平与对照组无显著差异。我们得出结论，在我们目前的方案下，缩乳术的自体血预存对围手术期即刻的患者并无益处。
