Chatelain P, Kündig F, Urban P, Meier B
Centre de cardiologie, Hôpital cantonal universitaire de Genève.
Schweiz Med Wochenschr. 1995 Mar 25;125(12):590-6.
Percutaneous balloon valvotomy is a recognized form of treatment of mitral stenosis. In Geneva between 1986 and 1993, 62 procedures were attempted in 60 patients (87% females) aged 48 +/- 17 years (12 to 80 years). Patient selection was based on symptoms (NYHA class), echocardiography (valve area, Boston score), and hemodynamics. 11 patients (18%) had undergone surgical commissurotomy in the past, 28 patients (47%) were in atrial fibrillation, and 12 patients (30%) had a history of peripheral emboli. Mild or moderate mitral insufficiency was present angiographically in 17 patients (28%) and echographically in 42 patients (70%). Esophageal echocardiography was performed in 37 patients (62%) before the procedure. In 52 patients (84%) a single balloon (Inoue technique) was used. Technical success was obtained in 59 procedures (95%). Following the procedure, mitral valve area increased from 1.1 +/- 0.3 to 1.8 +/- 0.3 cm2 (p < 0.0001) at echocardiography and from 1.1 +/- 0.3 to 1.9 +/- 0.5 cm2 (p < 0.0001) based on invasive hemodynamic data. There were 5 complications directly related to the procedure. In two cases cardiac tamponade developed, one after pericardial perforation during the transseptal approach and one because of left ventricular perforation. The second patient required surgical treatment. In two other cases, a moderate pericardial effusion without clinical consequences was observed. In one case the venous sheath malfunctioned, rendering surgical repair of the right femoral vein necessary. A residual atrial septal defect was observed at echography in 13 patients (22%). Mitral insufficiency was increased in 6 patients (10%) angiographically and in 9 patients (15%) at echocardiography.(ABSTRACT TRUNCATED AT 250 WORDS)
经皮球囊瓣膜成形术是二尖瓣狭窄公认的治疗方式。1986年至1993年期间,在日内瓦对60例患者(87%为女性)进行了62例该手术,患者年龄为48±17岁(12至80岁)。患者选择基于症状(纽约心脏协会分级)、超声心动图(瓣膜面积、波士顿评分)和血流动力学。11例患者(18%)过去曾接受过外科交界切开术,28例患者(47%)处于心房颤动状态,12例患者(30%)有外周栓塞史。血管造影显示17例患者(28%)存在轻度或中度二尖瓣关闭不全,超声心动图显示42例患者(70%)存在该情况。37例患者(62%)在手术前进行了食管超声心动图检查。52例患者(84%)使用了单个球囊(Inoue技术)。59例手术(95%)获得技术成功。术后,超声心动图显示二尖瓣瓣口面积从1.1±0.3增加至1.8±0.3 cm²(p<0.0001),基于有创血流动力学数据则从1.1±0.3增加至1.9±0.5 cm²(p<0.0001)。有5例并发症与手术直接相关。2例发生心脏压塞,1例在经房间隔穿刺过程中心包穿孔后发生,1例因左心室穿孔导致。第二例患者需要手术治疗。另外2例观察到有中度心包积液,但无临床后果。1例患者静脉鞘出现故障,需要对右股静脉进行手术修复。超声心动图检查发现13例患者(22%)存在残余房间隔缺损。血管造影显示6例患者(10%)二尖瓣关闭不全加重,超声心动图显示9例患者(15%)二尖瓣关闭不全加重。