Nasonova V A, Sigidin Ia A, Murav'ev Iu V, Lebedeva O I, Burtsev V I, Rashchupkina Z P, Krikunov V P, Kuzin A V, Nasonov E L, Chichasova N V
Ter Arkh. 1995;67(1):34-8.
A clinical trial of arthrotek (Searle) in 60 RA patients aged 16-77 years demonstrated its high anti-inflammatory activity in 47 of them. These patients have received a complete treatment course, 10 patients were not included in the overall estimations because of side affects (gastric pains and nausea) causing them to withdraw early in the treatment course, 3 patients were nonresponders. The responders experienced attenuation of joint pain, morning stiffness. Inflammation in some joints declined, the articular index decreased.
一项针对60名年龄在16至77岁的类风湿性关节炎(RA)患者开展的关于阿罗刻(塞尔公司生产)的临床试验表明,其中47名患者显示出该药物具有高度抗炎活性。这些患者接受了完整的治疗疗程,10名患者因出现副作用(胃痛和恶心)在疗程早期退出而未纳入总体评估,3名患者无反应。有反应的患者关节疼痛、晨僵症状减轻。部分关节的炎症减退,关节指数下降。