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[长期接触氟的工人甲状腺与免疫状态的相互关系]

[The interrelationship of the thyroid and immune statuses of workers with long-term fluorine exposure].

作者信息

Balabolkin M I, Mikhaĭlets N D, Lobovskaia R N, Chernousova N V

出版信息

Ter Arkh. 1995;67(1):41-2.

PMID:7709355
Abstract

Thyroid and immune statuses were studied in workers continuously exposed to fluorine. The examinees with euthyroid condition had immune disorders with an allergic tendency (increased number of B-lymphocytes, immunoglobulins A). In workers with subclinical hypothyrosis (tri-iodothyronine reduced in 51%), the immune alterations were more evident, T-lymphocytes count rose, but their functional activity declined, indicating impaired cooperation of immunocytes as a result of imperfect control under low concentrations of tri-iodothyronine.

摘要

对持续接触氟的工人的甲状腺和免疫状况进行了研究。甲状腺功能正常的受检者存在具有过敏倾向的免疫紊乱(B淋巴细胞、免疫球蛋白A数量增加)。在亚临床甲状腺功能减退的工人中(51%的人三碘甲状腺原氨酸降低),免疫改变更为明显,T淋巴细胞计数上升,但其功能活性下降,这表明在低浓度三碘甲状腺原氨酸控制不完善的情况下,免疫细胞之间的协作受损。

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