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院外心肺复苏术后神经功能预后的早期判定

Early determination of neurological outcome after prehospital cardiopulmonary resuscitation.

作者信息

Berek K, Lechleitner P, Luef G, Felber S, Saltuari L, Schinnerl A, Traweger C, Dienstl F, Aichner F

机构信息

Department of Neurology, University Hospital Innsbruck, Austria.

出版信息

Stroke. 1995 Apr;26(4):543-9. doi: 10.1161/01.str.26.4.543.

DOI:10.1161/01.str.26.4.543
PMID:7709394
Abstract

BACKGROUND AND PURPOSE

Although there are various methods of determining neurological prognosis after cardiopulmonary resuscitation, the final outcome of patients often remains unclear for quite a long time.

METHODS

We investigated 30 consecutively admitted patients who had been successfully resuscitated by the team of the local mobile intensive care unit after cardiac arrest. Determinations of the period of anoxia and of the cardiopulmonary resuscitation time, clinical investigation, echocardiography, electroencephalography, evoked potentials, magnetic resonance imaging, and magnetic resonance spectroscopy were performed.

RESULTS

Demonstration of brain lactate in proton magnetic resonance spectroscopy (P < .01) and absent N20 waves in short-latency somatosensory evoked potentials (P < .01) proved to be significant in terms of a poor prognosis. Correlations between both duration of anoxia and cardiopulmonary resuscitation time and neurological outcome could be shown as well (both P < .05).

CONCLUSIONS

Proton magnetic resonance spectroscopy and short-latency evoked potentials are of great benefit in the prognostic evaluation after cardiopulmonary resuscitation.

摘要

背景与目的

尽管有多种确定心肺复苏后神经功能预后的方法,但患者的最终结局在很长一段时间内往往仍不明确。

方法

我们调查了30例因心脏骤停后由当地移动重症监护病房团队成功复苏的连续入院患者。进行了缺氧时间和心肺复苏时间的测定、临床检查、超声心动图、脑电图、诱发电位、磁共振成像和磁共振波谱分析。

结果

质子磁共振波谱显示脑乳酸(P <.01)以及短潜伏期体感诱发电位中N20波缺失(P <.01)在预后不良方面具有显著意义。缺氧持续时间和心肺复苏时间与神经功能结局之间也存在相关性(均P <.05)。

结论

质子磁共振波谱和短潜伏期诱发电位在心肺复苏后的预后评估中具有很大益处。

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