角膜移植术后七年圆锥角膜复发的组织学证据。

Histologic evidence of recurrent keratoconus seven years after keratoplasty.

作者信息

Kremer I, Eagle R C, Rapuano C J, Laibson P R

机构信息

Department of Ophthalmology, Beilinson Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

出版信息

Am J Ophthalmol. 1995 Apr;119(4):511-2. doi: 10.1016/s0002-9394(14)71239-5.

DOI:10.1016/s0002-9394(14)71239-5

PMID:7709977

Abstract

PURPOSE/METHODS: A 42-year-old patient with keratoconus developed clinical signs of recurrent keratoconus in her right corneal graft seven years after the first keratoplasty was performed. She underwent successful corneal regrafting.

RESULTS/CONCLUSIONS: The histopathologic examination of the corneal button disclosed typical findings of keratoconus, including breaks in Bowman's layer filled with connective tissue or epithelium. These histologic findings in the corneal graft support our clinical diagnosis of keratoconus. However, the pathogenesis of this complication is still not clear and further research is needed.

摘要

目的/方法：一名42岁圆锥角膜患者在首次角膜移植术后7年，其右眼角膜移植片出现复发性圆锥角膜的临床体征。她接受了成功的角膜再次移植。

结果/结论：对角膜植片的组织病理学检查发现了圆锥角膜的典型表现，包括Bowman层断裂，内有结缔组织或上皮。角膜移植片中的这些组织学表现支持我们对圆锥角膜的临床诊断。然而，这种并发症的发病机制仍不清楚，需要进一步研究。