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Treatment of progressive outer retinal necrosis with sorivudine.

作者信息

Pinnolis M K, Foxworthy D, Kemp B

机构信息

Visual Services Department, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.

出版信息

Am J Ophthalmol. 1995 Apr;119(4):516-7. doi: 10.1016/s0002-9394(14)71242-5.

DOI:10.1016/s0002-9394(14)71242-5
PMID:7709980
Abstract

PURPOSE/METHODS: We examined a patient with progressive outer retinal necrosis, which is presumably caused by the varicella-zoster virus in patients with the acquired immunodeficiency syndrome.

RESULTS/CONCLUSIONS: The patient was successfully treated with a combination of intravitreal ganciclovir and oral sorivudine. Treatment for progressive outer retinal necrosis has been disappointing; both acyclovir and ganciclovir have had only limited success. Sorivudine, a new antiviral medication with activity against varicella-zoster virus, may represent an effective alternative treatment for retinal necrosis.

摘要

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