Suppr超能文献

A new rapid method for the analysis of catecholic tetrahydroisoquinolines from biological samples by gas chromatography/mass spectrometry.

作者信息

Haber H, Haber H M, Melzig M F

机构信息

Research Institute for Molecular Pharmacology, Berlin, Germany.

出版信息

Anal Biochem. 1995 Jan 1;224(1):256-62. doi: 10.1006/abio.1995.1038.

DOI:10.1006/abio.1995.1038
PMID:7710080
Abstract

A new method for the analysis of tetrahydroisoquinolines (TIQ) from biological materials is described. The method combines extraction and acylation of the TIQs from urine in a one-step procedure followed by analysis by gas chromatography/mass spectrometry. By this extractive derivatization method, a decrease of the extraction time, to speed up sample preparation in order to minimize oxidative side reaction, has been achieved. The detection limits for the analysis of salsolinol and salsolin in urine were 10 fmol/ml sample volume. Tetrahydropapaveroline could only be detected in spiked urine samples with a detection limit of 1 pmol/ml urine. The method is not only restricted to urine samples, but can also be applied to a variety of tissue types, including blood components.

摘要

相似文献

1
A new rapid method for the analysis of catecholic tetrahydroisoquinolines from biological samples by gas chromatography/mass spectrometry.
Anal Biochem. 1995 Jan 1;224(1):256-62. doi: 10.1006/abio.1995.1038.
2
Estimation of the in vivo concentration of salsolinol and tetrahydropapaveroline in rat brain after the administration of ethanol.给予乙醇后大鼠脑内萨罗啉醇和四氢罂粟碱体内浓度的测定。
Subst Alcohol Actions Misuse. 1980;1(3):317-22.
3
Analysis of salsolinol and salsoline in biological samples using deuterium-labelled internal standards and gas chromatography--mass spectrometry.使用氘标记内标和气相色谱-质谱联用技术分析生物样品中的萨索林醇和萨索灵。
J Chromatogr. 1980 Jul 11;183(1):17-24. doi: 10.1016/s0378-4347(00)81393-6.
4
Pictet-Spengler condensation products, stress and alcoholism: some clinical overtones.Pictet-Spengler缩合产物、应激与酒精中毒：一些临床弦外之音
Prog Clin Biol Res. 1982;90:215-26.
5
Precise GC/MS assays for salsolinol and tetrahydropapaveroline: the question of artifacts and dietary sources and the influence of alcohol.
Prog Clin Biol Res. 1985;183:77-84.
6
Simultaneous gas chromatographic-mass spectrometric determination of dopamine, norsalsolinol and salsolinol enantiomers in brain samples of a large human collective.同时气相色谱-质谱法测定大量人类群体脑样本中的多巴胺、去甲萨索利诺醇和萨索利诺醇对映体。
Cell Mol Biol (Noisy-le-grand). 2003 Jul;49(5):837-49.
7
Resolution of catecholic tetrahydroisoquinoline enantiomers and the determination of R- and S-salsolinol in biological samples by gas chromatography-mass spectrometry.儿茶酚四氢异喹啉对映体的拆分及生物样品中R-和S-萨索林醇的气相色谱-质谱测定
J Chromatogr B Biomed Appl. 1995 Oct 20;672(2):179-87. doi: 10.1016/0378-4347(95)00213-3.
8
Identification and quantification of 1-carboxysalsolinol and salsolinol in biological samples by gas chromatography--mass spectrometry.气相色谱-质谱联用法定量分析生物样品中1-羧基去甲骆驼蓬碱和去甲骆驼蓬碱
J Chromatogr. 1985 Sep 13;343(1):1-8. doi: 10.1016/s0378-4347(00)84562-4.
9
Determination of the (R)- and (S)-enantiomers of salsolinol and N-methylsalsolinol by use of a chiral high-performance liquid chromatographic column.使用手性高效液相色谱柱测定萨索利诺和N-甲基萨索利诺的（R）-和（S）-对映体。
J Chromatogr B Biomed Appl. 1995 Aug 4;670(1):47-54. doi: 10.1016/0378-4347(95)00136-7.
10
Assay for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods with ion-pair high-performance liquid chromatography using beta-cyclodextrin as a chiral mobile phase additive.采用β-环糊精作为手性流动相添加剂，通过离子对高效液相色谱法测定生物样品和食品中萨索林醇的（R）-和（S）-对映体。
J Chromatogr B Biomed Sci Appl. 1997 Feb 21;689(2):313-20. doi: 10.1016/s0378-4347(96)00359-3.

引用本文的文献

1
Computational Modeling of Inclusion Complexes of β-Cyclodextrin with enantiomers of Salsolinol, N-Methyl-Salsolinol, and 1-Benzyl-Tetrahydroisoquinoline.β-环糊精与沙罗啉醇、N-甲基沙罗啉醇和1-苄基-四氢异喹啉对映体包合物的计算模型
Int J Quantum Chem. 2009;109(1):81-90. doi: 10.1002/qua.21852.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验