大鼠妊娠和哺乳期小肠各段的形态学适应性变化

Morphological adaptive changes of small intestinal tract regions due to pregnancy and lactation in rats.

作者信息

Prieto R M, Ferrer M, Fe J M, Rayó J M, Tur J A

机构信息

Department of Fundamental Biology and Health Science, University of Balearic Islands, Palma de Mallorca, Spain.

出版信息

Ann Nutr Metab. 1994;38(5):295-300. doi: 10.1159/000177824.

DOI:10.1159/000177824

PMID:7710264

Abstract

In order to know the adaptive changes of small intestine regions (duodenum, and proximal, medial and distal jejunum-ileum) due to the reproductive stage (virgin, pregnancy and lactation), the weight, mucosal proportion, mucosal DNA and protein contents and protein/DNA ratio in female Wistar rats were measured. Pregnancy induces hypertrophy of the proximal half of the small intestine (duodenum and proximal jejunum-ileum), whereas lactation induces hyperplasia in all small intestinal regions and also hypertrophy but only in the duodenum.

摘要

为了解雌性Wistar大鼠小肠不同区域（十二指肠、空肠-回肠近端、中段和远端）在生殖阶段（未孕、妊娠和泌乳）的适应性变化，对其体重、黏膜比例、黏膜DNA和蛋白质含量以及蛋白质/DNA比值进行了测量。妊娠会导致小肠近端（十二指肠和空肠-回肠近端）肥大，而泌乳会导致所有小肠区域增生，也会导致肥大，但仅在十二指肠。