Gu H, Rong L, Sai J Y
Changhai Hospital, Second Military Medical College, Shanghai.
Zhonghua Fu Chan Ke Za Zhi. 1994 Dec;29(12):711-3, 760.
Plasma glucose and serum insulin in oral glucose tolerance test (OGTT) were measured in 40 patients with pregnancy induced hypertension (PIH) and 30 normal pregnancies. Compared with the controls, serum insulin concentration, plasma glucose and their area under the curve (AUC) increased in 15 patient with severe PIH, in 0.5, 1, 2, 3 hours postload (P < 0.05) of OGTT. The relationship between diastolic blood pressure and integrated area under the curve for serum insulin concentration (r = 0.35, P < 0.05) were observed in 15 patients with severe PIH. The results indicated that patients with severe PIH are insulin resistant and hyperinsulinemic after an oral glucose load.
对40例妊娠高血压综合征（PIH）患者和30例正常妊娠者进行了口服葡萄糖耐量试验（OGTT），测定了血浆葡萄糖和血清胰岛素水平。与对照组相比，15例重度PIH患者在OGTT负荷后0.5、1、2、3小时的血清胰岛素浓度、血浆葡萄糖及其曲线下面积（AUC）均升高（P<0.05）。在15例重度PIH患者中观察到舒张压与血清胰岛素浓度曲线下积分面积之间的关系（r=0.35，P<0.05）。结果表明，重度PIH患者口服葡萄糖负荷后存在胰岛素抵抗和高胰岛素血症。
