Variend S, Bax N M, van Gorp J
Department of Pathology, University Hospital, Utrecht, The Netherlands.
Histopathology. 1995 Jan;26(1):57-62. doi: 10.1111/j.1365-2559.1995.tb00621.x.
Infantile myofibromatosis, congenital fibrosarcoma and congenital/infantile haemangiopericytoma are generally considered distinct entities. Overlapping microscopic features between infantile myofibromatosis and congenital fibrosarcoma, and between infantile myofibromatosis and congenital/infantile haemangiopericytoma, however, have been noted, but not formally reported. This report concerns six neonatal tumours, each exhibiting more than one of the above patterns, supporting a histogenetic relationship among these entities. Immunohistochemistry for smooth muscle actin was found to be useful in the diagnosis of congenital/infantile haemangiopericytoma, and also served to support a histogenetic relationship with the other two entities under consideration.
婴儿肌纤维瘤病、先天性纤维肉瘤和先天性/婴儿血管外皮细胞瘤通常被认为是不同的实体。然而，婴儿肌纤维瘤病与先天性纤维肉瘤之间，以及婴儿肌纤维瘤病与先天性/婴儿血管外皮细胞瘤之间存在重叠的微观特征，但尚未有正式报道。本报告涉及6例新生儿肿瘤，每例均表现出上述多种模式，支持这些实体之间的组织发生学关系。发现平滑肌肌动蛋白免疫组化在先天性/婴儿血管外皮细胞瘤的诊断中有用，也有助于支持与其他两个相关实体的组织发生学关系。
