Phillips K A, McElroy S L, Hudson J I, Pope H G
McLean Hospital, Belmont, Mass., USA.
J Clin Psychiatry. 1995;56 Suppl 4:41-51; discussion 52.
Over the past century, body dysmorphic disorder (BDD), a preoccupation with an imagined or slight defect in appearance, has been hypothesized to be related to obsessive-compulsive disorder (OCD). More recently, BDD has also been hypothesized to be a form of affective spectrum disorder. Affective spectrum disorder refers to a family of disorders postulated to have a common pathophysiologic abnormality. This grouping of disorders has been identified on the basis of their response to pharmacologic treatments and is supported by comorbidity and family studies. Available data suggest that BDD should be considered a candidate form of affective spectrum disorder--a disorder that may eventually be demonstrated to belong to this family of disorders. Available data also strongly support the hypothesis that BDD is an obsessive-compulsive spectrum disorder. Because OCD itself has been hypothesized to be an affective spectrum disorder, BDD may be more narrowly conceptualized as an obsessive-compulsive spectrum disorder and more broadly as a candidate form of affective spectrum disorder.
在过去的一个世纪里,躯体变形障碍(BDD),即过度关注想象中的或轻微的外表缺陷,一直被认为与强迫症(OCD)有关。最近,BDD也被认为是情感谱系障碍的一种形式。情感谱系障碍是指一类被假定存在共同病理生理异常的疾病。这类疾病是根据它们对药物治疗的反应来确定的,并得到了共病和家族研究的支持。现有数据表明,BDD应被视为情感谱系障碍的一种候选形式——一种最终可能被证明属于这类疾病的病症。现有数据也有力地支持了BDD是一种强迫谱系障碍的假说。由于强迫症本身就被认为是一种情感谱系障碍,BDD可能更狭义地被概念化为一种强迫谱系障碍,更广义地被视为情感谱系障碍的一种候选形式。