电位滴定法测定双阴离子化合物的分配系数和分布系数
Potentiometric determination of the partition and distribution coefficients of dianionic compounds.
作者信息
Clarke F H, Cahoon N M
机构信息
ChemClarke, Inc., Califon, NJ 07830.
出版信息
J Pharm Sci. 1995 Jan;84(1):53-4. doi: 10.1002/jps.2600840113.
PMID:7714744
Abstract
The potentiometric determination of the partition and distribution coefficients of two dianionic hexapeptide derivatives is described. For each of these compounds, the partition coefficient of the dianion makes the largest contribution to the distribution coefficient at pH 7.4.
摘要
描述了两种二阴离子六肽衍生物的分配系数和分布系数的电位测定法。对于每种化合物，在pH 7.4时，二阴离子的分配系数对分布系数的贡献最大。
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