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岛状皮瓣尿道成形术后重建新尿道的功能特征

Functional characteristics of the reconstructed neourethra after island flap urethroplasty.

作者信息

Jayanthi V R, McLorie G A, Khoury A E, Churchill B M

机构信息

Division of Urology, Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

J Urol. 1995 May;153(5):1657-9.

PMID:7715002
Abstract

To test the neourethra objectively in cases judged to be clinical successes after transverse island flap hypospadias repair, we analyzed uroflowmetry data (peak flow, voided volume and ultrasonically determined post-void residuals) after repair. Patients were included if they were old enough to void volitionally and flow data were available after fistula or stricture repair. Flow data were then plotted on previously published age-dependent nomograms from normal controls. Of 80 boys available for study 51 required no secondary procedures, 16 subsequently underwent fistula repair and 13 had strictures opened. After all primary and secondary procedures 55 patients (69%) had peak flows within the normal range and 25 (31%) had peak flows below the normal range. Of the 51 boys who never had fistulas and/or strictures 37 (73%) had normal flows while 18 of 29 (62%) who underwent fistula and/or stricture repairs had normal flows (p < 0.05). Residual volume was less than 10% of voided volume in 44 of the 51 boys who clinically had no problems postoperatively, in 8 of the 13 who had strictures opened and in 15 of the 16 who underwent fistula repairs. We conclude that the neourethra is functionally equivalent to a normal urethra in most boys after transverse flap urethroplasty. A majority of boys will have normal flow even after stricture or fistula repair.

摘要

为了客观地评估横行岛状皮瓣修复尿道下裂术后临床判定为成功病例的新尿道情况,我们分析了修复术后的尿流率数据(峰值尿流率、排尿量以及超声测定的残余尿量)。如果患者年龄足够大能够自主排尿且在瘘管或狭窄修复术后有尿流数据,就将其纳入研究。然后将尿流数据绘制在先前发表的来自正常对照的年龄相关列线图上。在80名可供研究的男孩中,51名无需二次手术,16名随后接受了瘘管修复,13名进行了狭窄切开术。在所有一期和二期手术后,55名患者(69%)的峰值尿流率在正常范围内,25名患者(31%)的峰值尿流率低于正常范围。在从未发生过瘘管和/或狭窄的51名男孩中,37名(73%)尿流正常,而在接受瘘管和/或狭窄修复的29名男孩中,18名(62%)尿流正常(p<0.05)。在51名术后临床无问题的男孩中,44名的残余尿量小于排尿量的10%;在13名进行了狭窄切开术的男孩中,8名是这样;在16名接受了瘘管修复的男孩中,15名是这样。我们得出结论,在大多数接受横行皮瓣尿道成形术的男孩中,新尿道在功能上等同于正常尿道。即使在狭窄或瘘管修复术后,大多数男孩的尿流也将正常。

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