Singleton R J, Petersen K M, Berner J E, Schulte E, Chiu K, Lilly C M, Hughes E A, Bulkow L R, Nix T L
Alaska Area Native Health Service, Anchorage 99501, USA.
Pediatr Infect Dis J. 1995 Jan;14(1):26-30. doi: 10.1097/00006454-199501000-00005.
To characterize the epidemiology of Alaska Native children hospitalized for respiratory syncytial virus infections, we reviewed records of hospitalizations during the winter seasons of 1991 to 1992 and 1992 to 1993 at a hospital in Anchorage and a rural hospital in the Yukon Kuskokwim Delta (YKD) region of southwestern Alaska. The median age of hospitalization for respiratory syncytial virus infection was 2 months of age for YKD residents and 4.5 months for Anchorage residents. Sixteen percent of the hospitalized YKD children were less than 1 month of age, whereas the same was true for only 3% of the Anchorage children. Eight percent of the YKD patients required mechanical ventilation, whereas none of the Anchorage patients required ventilation. The median hospital stay was 4.8 days for YKD patients and 3.2 days for Anchorage patients. Hospitalization rates for infants less than 1 year of age were 33/1000 for Alaska Natives in Anchorage and 100/1000 for those in the YKD region. The extremely high hospitalization rate, especially among very young infants in the rural YKD region, points to a need for early preventive efforts.
为了描述因呼吸道合胞病毒感染而住院的阿拉斯加原住民儿童的流行病学特征，我们回顾了1991年至1992年以及1992年至1993年冬季期间，阿拉斯加安克雷奇市一家医院以及阿拉斯加西南部育空-库斯科基姆三角洲（YKD）地区一家乡村医院的住院记录。YKD地区居民因呼吸道合胞病毒感染住院的中位年龄为2个月，安克雷奇市居民为4.5个月。YKD地区住院儿童中有16%年龄小于1个月，而安克雷奇市儿童中这一比例仅为3%。YKD地区8%的患者需要机械通气，而安克雷奇市患者无人需要通气。YKD地区患者的中位住院时间为4.8天，安克雷奇市患者为3.2天。安克雷奇市1岁以下阿拉斯加原住民婴儿的住院率为33/1000，YKD地区为100/1000。极高的住院率，尤其是在YKD地区农村的非常年幼的婴儿中，表明需要尽早开展预防工作。
