Marano I, Della Noce M, Stagni V, Belfiore G, Sodano A, Belli G, Santangelo M
Istituto di Scienze Radiologiche, Università Federico II, Napoli.
Radiol Med. 1995 Jan-Feb;89(1-2):94-9.
The diagnostic accuracy of Magnetic Resonance Imaging (MRI) in the preoperative staging of unifocal hepatocellular carcinoma (HCC) was investigated and compared with that of ultrasonography (US) and Computed Tomography (CT). Eighteen patients with focal HCCs underwent MRI, CT and US scans before surgery. In all cases the histopathologic diagnosis was made with CT-guided fine-needle aspiration biopsy (FNAB). The diagnostic accuracy of each imaging modality was investigated with the assessment of three parameters thought to be of the utmost importance for surgical planning, i.e., lesion unifocality, the presence of a capsule and finally vascular involvement. MRI proved to be more sensitive than CT in demonstrating both lesion unifocality (100% vs. 94.4%) and the presence of a capsule (100% vs. 71.4%). In 2 of 18 patients some blood vessels were involved, which was clearly demonstrated only by MRI, CT missing it. Both MRI and CT had 100% specificity in the detection of a perilesional capsule and of vascular involvement. To conclude, MRI exhibited higher diagnostic accuracy than US and CT, thus confirming its major role in the preoperative staging of unifocal HCCs.
研究了磁共振成像（MRI）在单灶性肝细胞癌（HCC）术前分期中的诊断准确性，并与超声检查（US）和计算机断层扫描（CT）进行比较。18例局灶性HCC患者在手术前接受了MRI、CT和US扫描。所有病例均通过CT引导下细针穿刺活检（FNAB）进行组织病理学诊断。通过评估三个被认为对手术规划至关重要的参数，即病变的单灶性、包膜的存在以及最终的血管受累情况，来研究每种成像方式的诊断准确性。在显示病变单灶性（100%对94.4%）和包膜存在（100%对71.4%）方面，MRI被证明比CT更敏感。18例患者中有2例存在一些血管受累情况，仅MRI能清楚显示，CT则未发现。在检测病灶周围包膜和血管受累方面，MRI和CT的特异性均为100%。总之，MRI显示出比US和CT更高的诊断准确性，从而证实了其在单灶性HCC术前分期中的主要作用。
