[成人上皮型肝母细胞瘤]

[Epithelial hepatoblastomas in the adult].

作者信息

Mondragón Sánchez R, Bernal Maldonado R, Sada Navarro L A, Hernández A I, Hurtado Andrade H, Cortés Espinoza T, Sánchez Cisneros R

机构信息

Departamento de Cirugía, Centro Hospitalario 20 de Noviembre, ISSTE, México D.F.

出版信息

Rev Gastroenterol Mex. 1994 Jul-Sep;59(3):231-5.

PMID:7716366

Abstract

Hepatoblastoma is the most frequent primary malignant liver neoplasm in childhood; in adults it is extremely rare and only 27 cases have been published. The prognosis of this neoplasm is poor because it is usually discovered late. Surgery, chemotherapy and liver transplantation have been tried with poor results. We present two adult patients who were diagnosed with an epithelial hepatoblastoma. The pathogenesis, histologic features and current management is reviewed.

摘要

肝母细胞瘤是儿童期最常见的原发性肝脏恶性肿瘤；在成人中极为罕见，仅有27例病例被报道。该肿瘤的预后较差，因为它通常发现较晚。手术、化疗和肝移植都曾尝试过，但效果不佳。我们报告两例被诊断为上皮型肝母细胞瘤的成年患者。本文对其发病机制、组织学特征及当前治疗方法进行了综述。