Yeshurun D, Gotto A M
Department of Medicine, Baylor College of Medicine, Houston, Tex. 77030, USA.
South Med J. 1995 Apr;88(4):379-91.
Several forms of dyslipidemia are associated with premature coronary artery disease (CAD) and other vascular disease. These include elevated low-density lipoprotein cholesterol, low levels of high-density lipoprotein cholesterol, and elevated triglyceride. Because of the high incidence of CAD in many Western countries, including the United States, guidelines for managing dyslipidemia and reducing the risk of CAD have been promulgated. The National Cholesterol Education Program (NCEP) of the National Institutes of Health recently released revised guidelines for the treatment of adults with dyslipidemia, as did the European Atherosclerosis Society. Although the two reports differ in emphasis, both recommend routine screening of adults to identify specific individuals at high risk for future CAD events.
几种形式的血脂异常与早发性冠状动脉疾病(CAD)及其他血管疾病相关。这些包括低密度脂蛋白胆固醇升高、高密度脂蛋白胆固醇水平降低以及甘油三酯升高。由于在包括美国在内的许多西方国家CAD发病率较高,因此已经颁布了管理血脂异常和降低CAD风险的指南。美国国立卫生研究院的国家胆固醇教育计划(NCEP)最近发布了针对患有血脂异常的成年人的修订治疗指南,欧洲动脉粥样硬化学会也发布了相关指南。尽管两份报告重点有所不同,但都建议对成年人进行常规筛查,以识别未来发生CAD事件的高风险特定个体。