Southerland J H, Patton L L
Department of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA.
Spec Care Dentist. 1993 Sep-Oct;13(5):200-4. doi: 10.1111/j.1754-4505.1993.tb01496.x.
Spontaneous osteoradionecrosis of the mandible is an oral complication of radiation therapy. Bone necrosis, unrelated to trauma or infection, is more common when high doses of radiation, including interstitial implants, are delivered to a large bone volume. Management provides a challenge for the dentist and patient. When conservative, non-surgical treatment is unsuccessful, surgical debridement with adjunctive hyperbaric oxygen therapy and eventual mandibular resection may result. A case of spontaneous osteoradionecrosis is described which underscores the clinical course of the disease and treatment outcomes.
下颌骨放射性骨坏死是放射治疗的一种口腔并发症。与创伤或感染无关的骨坏死，在包括组织间植入物在内的高剂量辐射作用于较大骨体积时更为常见。其治疗对牙医和患者来说都是一项挑战。当保守的非手术治疗失败时，可能需要进行手术清创并辅助高压氧治疗，最终可能需要进行下颌骨切除术。本文描述了一例自发性放射性骨坏死病例，突出了该疾病的临床病程和治疗结果。
