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口腔鳞状细胞癌放疗后下颌骨切开部位骨不连

Non-union of mandibulotomy sites following irradiation for squamous cell carcinoma of the oral cavity.

作者信息

Altman K, Bailey B M

机构信息

Department of Oral and Maxillofacial Surgery, Ashford Hospital, Middlesex.

出版信息

Br J Oral Maxillofac Surg. 1996 Feb;34(1):62-5. doi: 10.1016/s0266-4356(96)90138-2.

Abstract

Mandibulotomy improves surgical access to the oral cavity for the resection of tumours. Non-union of the mandibulotomy due to osteoradionecrosis has been observed in five patients with oral squamous cell carcinoma, all of whom had radiotherapy either as the primary modality of treatment or for tumour recurrence. This paper reports this series of patients, discusses their management and highlights the risk factors for the development of osteoradionecrosis.

摘要

下颌骨切开术可改善手术入路,便于切除口腔肿瘤。在5例口腔鳞状细胞癌患者中观察到因放射性骨坏死导致的下颌骨切开术骨不连,所有这些患者均接受过放疗,放疗作为主要治疗方式或用于肿瘤复发。本文报告了这组患者,讨论了他们的治疗方法,并强调了放射性骨坏死发生的危险因素。

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