Zhao B, Dierichs R, Harrach-Ruprecht B, Winterhorff H
Platelet Research Unit, University of Münster, Germany.
Am J Hematol. 1995 Apr;48(4):285-7. doi: 10.1002/ajh.2830480417.
Oxidized low-density lipoprotein (LDL) induces a release of serotonin from morphologically resting platelets and shape changed platelets. This suggests that oxidized LDL, a newly reported weak agonist, contributes to atherogenesis and thrombogenesis by stimulating platelets.
氧化型低密度脂蛋白(LDL)可诱导形态正常的血小板和发生形态改变的血小板释放5-羟色胺。这表明,氧化型LDL作为一种新报道的弱激动剂,通过刺激血小板而促进动脉粥样硬化形成和血栓形成。