Trocki O, Michelini J A, Robbins S T, Eichelberger M R
Children's National Medical Center, Washington, DC, USA.
Burns. 1995 Feb;21(1):17-23. doi: 10.1016/0305-4179(95)90775-u.
Early enteral feeding and high protein nutrition have been advocated for burned patients. The safety and efficacy of early high protein nasogastric feeding (NG) have not been evaluated in very young children. The present study evaluated such feeding in children less than 3 years old with smaller burns (8-25 per cent of total body surface area). Children (n = 10) were able to tolerate high protein intake without detrimental effects. The incidences of gastrointestinal complications related to NG feeding were low. The children needed approximately 2 weeks of supplemental NG feeding which provided two-thirds of total energy intake and three-fourths of protein intake. In spite of smaller burns, the mean measured resting metabolic expenditure (REE) was 1.3 x predicted REE. The mean energy intake of 92 per cent of recommended daily allowances (RDA) for energy or 1.7 x predicted REE was able to maintain body weight. The mean protein intake was 4.3 g/kg/day with a non-protein calorie ratio of 114:1. During the first week postburn, plasma concentrations of prealbumin, albumin and transferrin were low. The high protein intake was able to raise these visceral proteins to normal ranges. These results indicate that early NG feeding is safe and efficacious for achieving increased energy intake and improved protein status in very young children.
早期肠内喂养和高蛋白营养已被推荐用于烧伤患者。早期高蛋白鼻胃管喂养(NG)在幼儿中的安全性和有效性尚未得到评估。本研究评估了这种喂养方式在烧伤面积较小(占体表面积8%-25%)的3岁以下儿童中的效果。10名儿童能够耐受高蛋白摄入且无不良影响。与鼻胃管喂养相关的胃肠道并发症发生率较低。这些儿童需要大约2周的鼻胃管补充喂养,补充的能量占总能量摄入的三分之二,蛋白质占四分之三。尽管烧伤面积较小,但测得的平均静息代谢能量消耗(REE)为预测REE的1.3倍。92%的推荐每日能量摄入量(RDA)或1.7倍预测REE的平均能量摄入能够维持体重。平均蛋白质摄入量为4.3克/千克/天,非蛋白质热量比为114:1。烧伤后第一周,前白蛋白、白蛋白和转铁蛋白的血浆浓度较低。高蛋白摄入能够将这些内脏蛋白提高到正常范围。这些结果表明,早期鼻胃管喂养对于增加幼儿能量摄入和改善蛋白质状况是安全有效的。