[实验性内淋巴积水时内淋巴和外淋巴中钙离子浓度的变化]

[The changes of Ca++ concentrations of endolymph and perilymph of the experimental endolymphatic hydrops].

作者信息

Wang Q, Zhang L

机构信息

PUMC Hospital, Beijing.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1994;29(5):263-5.

PMID:7718286

Abstract

The changes of Ca++ concentrations of endo- and perilymph were determined by using atomic absorption spectrophotometry in the guinea pig model which endolymphatic sac and duct were surgically obliterated one month ago. The results showed that the Ca++ concentrations of endolymph of hydropic ear was 0.181+0.129 mmol/L (n = 9), and that of the control group was 0.020+0.014 mmol/L (n = 10). The paired t test (P < 0.01) showed significant difference. In perilymph, the concentrations of Ca++ of hydropic ear was 0.679+0.340 mmol/L (n = 10), and that of the control ears was 0.730+0.385 mmol/L (n = 10). The paired t-test (P > 0.05) showed no significant difference. The principle of the increase of Ca++ concentrations in the endolymphatic hydrops was also discussed.

摘要

采用原子吸收分光光度法，在豚鼠模型中测定了1个月前手术闭塞内淋巴囊和内淋巴管后内淋巴和外淋巴中钙离子浓度的变化。结果显示，患耳内淋巴中钙离子浓度为0.181±0.129 mmol/L（n = 9），对照组为0.020±0.014 mmol/L（n = 10）。配对t检验（P < 0.01）显示差异有统计学意义。在外淋巴中，患耳钙离子浓度为0.679±0.340 mmol/L（n = 10），对照耳为0.730±0.385 mmol/L（n = 10）。配对t检验（P > 0.05）显示差异无统计学意义。本文还讨论了内淋巴积水时钙离子浓度升高的机制。