Makino H, Nagake Y, Moriwaki K, Hirakawa S, Katayama T, Yanai H, Takahashi K, Akagi T, Ota Z
Third Department of Internal Medicine, Okayama University Medical School.
Intern Med. 1995 Jan;34(1):24-7. doi: 10.2169/internalmedicine.34.24.
A 73-year-old woman was admitted to receive radiation treatment for uterine cervical cancer, however a complex series of events ensued, leading to death. She developed an acute exacerbation of polymyositis complicated by thrombotic thrombocytopenic purpura, rhabdomyolysis and acute renal failure. Radiation therapy may have produced an immune disturbance leading to the acute exacerbation of polymyositis. Auto-immune-mediated endothelial damage might have triggered a series of events leading to thrombotic thrombocytopenic purpura. Rhabdomyolysis seemed to be the main cause of acute renal failure.
一名73岁女性因子宫颈癌入院接受放射治疗，但随后发生了一系列复杂事件，导致死亡。她出现了多发性肌炎急性加重，并伴有血栓性血小板减少性紫癜、横纹肌溶解和急性肾衰竭。放射治疗可能引发了免疫紊乱，导致多发性肌炎急性加重。自身免疫介导的内皮损伤可能触发了一系列导致血栓性血小板减少性紫癜的事件。横纹肌溶解似乎是急性肾衰竭的主要原因。
