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支气管灌洗细胞学检查中新型隐球菌的检测:4例报告

Detection of Cryptococcus neoformans in bronchial lavage cytology: report of four cases.

作者信息

Maesaki S, Kohno S, Mashimoto H, Araki J, Asai S, Hara K

机构信息

Sasebo General Hospital.

出版信息

Intern Med. 1995 Jan;34(1):54-7. doi: 10.2169/internalmedicine.34.54.

DOI:10.2169/internalmedicine.34.54
PMID:7718982
Abstract

Four cases of pulmonary cryptococcosis were diagnosed by cytological detection of Cryptococcus neoformans in bronchial lavage. Three patients had underlying diseases, but not HIV infection. The chest X-rays showed 2 patients with nodular lesions and 2 with cavitary lesions. The cryptococcal antigen in the serum was positive in all four patients. In the cytology of bronchial lavage, Cryptococcus neoformans was detected after period-acid-Schiff (PAS) staining and was cultured in Sabouraud-dextrose agar. The cytology of bronchial lavage is useful for the rapid diagnosis of pulmonary cryptococcosis.

摘要

通过支气管灌洗中新型隐球菌的细胞学检测诊断出4例肺隐球菌病。3例患者有基础疾病,但未感染HIV。胸部X光显示2例患者有结节性病变,2例有空洞性病变。所有4例患者血清中的隐球菌抗原均为阳性。在支气管灌洗的细胞学检查中,经高碘酸-希夫(PAS)染色后检测到新型隐球菌,并在沙氏葡萄糖琼脂上进行培养。支气管灌洗的细胞学检查有助于快速诊断肺隐球菌病。

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