支气管肺泡灌洗 fluid 进行隐球菌抗原常规检测的效用
Utility of routine testing of bronchoalveolar lavage fluid for cryptococcal antigen.
作者信息
Kralovic S M, Rhodes J C
机构信息
Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Ohio, USA.
出版信息
J Clin Microbiol. 1998 Oct;36(10):3088-9. doi: 10.1128/JCM.36.10.3088-3089.1998.
Abstract
All cryptococcal antigen (CrAg) testing performed at our institution between 1989 and 1994 was reviewed for utility of routinely testing of bronchoalveolar lavage fluid (BAL) for this antigen. Forty-two of 1,506 BAL specimens were positive. Seventeen of these were felt to represent false positives (sensitivity, 71%; positive predictive value, 0.59). The data on CrAg in cerebrospinal fluid and serum and the fungal culture and histological results of BAL specimens did not support continued, routine testing of BALs for CrAg to diagnose cryptococcosis.
摘要
回顾了1989年至1994年间在我们机构进行的所有隐球菌抗原（CrAg）检测，以评估对支气管肺泡灌洗（BAL）液进行该抗原常规检测的实用性。1506份BAL标本中有42份呈阳性。其中17份被认为是假阳性（敏感性为71%；阳性预测值为0.59）。脑脊液和血清中CrAg的数据以及BAL标本的真菌培养和组织学结果不支持继续对BAL进行CrAg常规检测以诊断隐球菌病。
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