Meyer G, Schiefer U, Dietz K, Wilhelm H
Abteilung für Pathophysiologie des Sehens und Neuroophthalmologie, Universitäts-Augenklinik Tübingen.
Ophthalmologe. 1995 Feb;92(1):61-70.
A new transportable miniaturized flicker test equipped with green LEDs is contrasted with the conventional Tübingen flicker test, based on brightness perception of intermittent white light. The results are compared with those of former studies. In this study we examined 45 eyes suffering from florid optic neuritis. Another group of 114 eyes were either normal (except minimal ametropia) or suffered from a non-inflammatory or non-refractive impairment of central visual function. In all groups only one eye of each subject was examined. Using the criteria of Trauzettel-Klosinski, the new miniaturized "green" flicker test for the detection of a florid optic neuritis showed a specificity of only 50.9% (83.3%) and a sensitivity of 91.1% (64.4%). (The corresponding results of the conventional Tübingen flicker test are shown in parentheses.) Alternatively, analyzing the data with the help of a logistic regression, the "green" flicker test turned out to have a specificity of 92.9% (93.8%) and a sensitivity of 60.5% (44.2%). For further examinations using the flicker test it is useful to consider the duration and reproducibility of each brightness match by repeating the test several times.
一种配备绿色发光二极管的新型便携式微型闪烁测试与传统的图宾根闪烁测试形成对比，后者基于对间歇性白光的亮度感知。将结果与以前的研究结果进行比较。在本研究中，我们检查了45只患有急性视神经炎的眼睛。另一组114只眼睛要么正常（除了轻微屈光不正），要么患有中枢视觉功能的非炎症性或非屈光性损害。在所有组中，每个受试者仅检查一只眼睛。根据特劳泽特尔 - 克洛辛斯基的标准，用于检测急性视神经炎的新型微型“绿色”闪烁测试显示特异性仅为50.9%（83.3%），灵敏度为91.1%（64.4%）。（传统图宾根闪烁测试的相应结果显示在括号中。）或者，借助逻辑回归分析数据，“绿色”闪烁测试的特异性为92.9%（93.8%），灵敏度为60.5%（44.2%）。对于使用闪烁测试的进一步检查，通过多次重复测试来考虑每次亮度匹配的持续时间和可重复性是很有用的。
