Fang J Q, Liu Y L, Mo X M
Zhejiang College, TCM, Hangzhou.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Oct;14(10):579-82.
Through the treatment of 65 cases of painful diseases with electroacupuncture, in comparing with the analgesic effect of contralateral stimulation (CS) and ipsilateral stimulation (IS), it was verified that IS and CS had the similar effect on pain-relieving, while CS was better in improving motor impairment. By testing the rat's pain threshold and recording the neuronal activity in the D-PAG, it was found that neither IS nor CS could increase the pain threshold in the unilateral D-PAG lesioned rats, and the excited neuronal discharge was recorded in the unilateral D-PAG by stimulating rat's Zusanli (ST 36) at each side. It indicates that IS and CS might share the same high level afferent pathway in acupuncture analgesia in CNS.
通过对65例疼痛性疾病患者进行电针治疗,比较对侧刺激(CS)和同侧刺激(IS)的镇痛效果,证实IS和CS在缓解疼痛方面效果相似,而CS在改善运动功能障碍方面更佳。通过测试大鼠的痛阈并记录中脑导水管周围背侧区(D-PAG)的神经元活动,发现无论是IS还是CS均不能提高单侧D-PAG损伤大鼠的痛阈,且在分别刺激大鼠双侧足三里(ST 36)时,在单侧D-PAG记录到神经元放电兴奋。这表明在中枢神经系统针刺镇痛中,IS和CS可能共用相同的高位传入通路。