Cao K, Shi X, Zhang Y, Wang Z, Hu K
PUMC Hospital, CAMS, Beijing.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1994 Dec;16(6):416-9.
In order to examine the characteristics of the auditory brainstem implant, an animal model with electrical stimulation of the cochlear nucleus in guinea pigs was created. Middle latency response (MLR) to pulsatile electrical stimulation of the cochlear nucleus was recorded from the auditory cortex with bipolar plantinumiridium electrodes and stereotaxic technique. The electrically and acoustically generated MLRs have a similar morphology though there are little differences in the latencies, wave intervals and dynamic ranges. The results indicated that the central auditory pathways can be activated by means of electrical stimulation. The safety of the brain tissue to the electrical stimulation are also discussed.
为了研究听觉脑干植入物的特性，建立了豚鼠耳蜗核电刺激动物模型。采用双极铂铱电极和立体定位技术，从听觉皮层记录对耳蜗核脉冲电刺激的中潜伏期反应（MLR）。电刺激和声音刺激产生的MLR形态相似，尽管在潜伏期、波间期和动态范围上存在细微差异。结果表明，电刺激可激活中枢听觉通路。还讨论了脑组织对电刺激的安全性。
