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[豚鼠听觉中潜伏期反应的地形图研究]

[Study of topographic mapping of the auditory middle latency response in the guinea pigs].

作者信息

Zhang Y, Jiang S, Gu R

机构信息

PLA General Hospital, Beijing.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1994;29(2):67-70.

PMID:7803091
Abstract

Topographic mapping techniques were applied to study the auditory middle latency response (MLR) in 10 awake guinea pigs. Fourteen holes (1mm in diameter) were drilled through the skull regions and epidural electrodes were fixed on the skull with the dental cement, then auditory MLR were recorded with 13 electrodes, and MLR brain maps were obtained with a concerto system. Our result supports the hypothesis of multiple MLR generators. The main components are wave A, wave B and wave C. The foci localise the temporal lobe contralateral to the stimulated ear. The other components are wave M- and wave M+. The foci localise parietal and occipital lobes. Each wave responds differently to procaine. The result suggests that wave A, wave M- and wave M+ are generated from the subcortex, while wave B, wave C generated from the cortex.

摘要

应用地形图绘制技术对10只清醒豚鼠的听觉中潜伏期反应(MLR)进行研究。在颅骨区域钻14个直径为1毫米的孔,用牙科水泥将硬膜外电极固定在颅骨上,然后用13个电极记录听觉MLR,并使用协奏曲系统获得MLR脑图谱。我们的结果支持多个MLR发生器的假说。主要成分是A波、B波和C波。其焦点位于受刺激耳对侧的颞叶。其他成分是M-波和M+波。其焦点位于顶叶和枕叶。每个波对普鲁卡因的反应不同。结果表明,A波、M-波和M+波由皮质下产生,而B波、C波由皮质产生。

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