[雷公藤总苷中三萜类化合物的研究]

[Studies on triterpenoids of total glucosides of tripterygium wilfordii].

作者信息

Zhang C, Yan Z, Chen Y, Zhang Y, Lü X

机构信息

Institute of Dermatology, CAMS, Nanjing.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1994 Dec;16(6):466-8.

PMID:7720147

Abstract

Three more triterpenoids were isolated from total glucosides of tripterygium wilfordii (T1). T16 and T17 were identified as salaspermic acid and as wilforlide B. T18 was a new compound. The structure of T18 was determined, as 3-oxo-22 alpha-hydroxy-delta 12-oleanen-29-oic acid by detail spectroscopic and chemical analysis, and named triptotriterpenonic acid A.

摘要

从雷公藤总苷（T1）中又分离出三种三萜类化合物。T16和T17分别被鉴定为柳杉酚酸和雷公藤内酯醇B。T18是一种新化合物。通过详细的光谱和化学分析确定T18的结构为3-氧代-22α-羟基-Δ12-齐墩果烷-29-酸，并命名为雷公三萜酸A。