Zhang D M, Yu D Q, Xie F Z
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.
Yao Xue Xue Bao. 1991;26(5):341-4.
Three triterpene compounds have been isolated from the roots of Tripterygium wilfordii Hook F. The structure of the new compound, 3-hydroxy-25-norfriedel-3, 1 (10)-dien-2-one-30 oic acid named tripterygone (III), and the identity of others, 3 beta, 22 beta-dihydroxy-delta 12-oleanen-29-oic acid (I) and 2 alpha, 3 alpha, 24-trihydroxy-delta 12-ursene-28-oic acid (II) have been established by spectral data and physical properties. Compound II was isolated for the first time from the title plant.
从雷公藤根中分离出三种三萜化合物。新化合物3-羟基-25-降-弗里德-3,1(10)-二烯-2-酮-30-酸(命名为雷公藤酮(III))的结构,以及其他两种化合物3β,22β-二羟基-Δ12-齐墩果烷-29-酸(I)和2α,3α,24-三羟基-Δ12-乌苏烷-28-酸(II),已通过光谱数据和物理性质得以确定。化合物II首次从该植物中分离得到。