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辐射诱导同染：事实还是虚构？

Radiation induced isostaining: fact or fiction?

作者信息

Gerner-Smidt P

出版信息

Chromosoma. 1978 Apr 25;66(3):281-5. doi: 10.1007/BF00330556.

DOI:10.1007/BF00330556
PMID:77215
Abstract

Two different experiments were set up to induce differential staining in M-1(1) cells or to induce isostaining in M-2 cells after gamma-irradiation of human lymphocytes. Neither of these two unusual staining patterns previously described by Luchnik and Porjadkova (1977) were observed. Possible explanations for this disagreement are discussed.

摘要

进行了两项不同的实验，以在人淋巴细胞经γ射线照射后诱导M-1(1)细胞出现差异染色或诱导M-2细胞出现同染。未观察到Luchnik和Porjadkova（1977年）先前描述的这两种异常染色模式中的任何一种。讨论了这种不一致的可能解释。

相似文献

1
Radiation induced isostaining: fact or fiction?辐射诱导同染：事实还是虚构？
Chromosoma. 1978 Apr 25;66(3):281-5. doi: 10.1007/BF00330556.
2
[Relation between the dynamics of the cell cycle and the frequency of chromosome aberrations in cultured irradiated human lymphocytes].[培养的受辐照人淋巴细胞中细胞周期动力学与染色体畸变频率之间的关系]
Tsitol Genet. 1986 Mar-Apr;20(2):97-102.
3
[The quantitative patterns in the yield of chromosome aberrations in a human lymphocyte culture under fractionated gamma-neutron irradiation at different stages of the mitotic cycle. The cytogenetic effects at the G0 stage].[在有丝分裂周期不同阶段进行分次γ-中子照射时人淋巴细胞培养中染色体畸变产率的定量模式。G0期的细胞遗传学效应]
Radiobiologiia. 1992 Jul-Aug;32(4):506-11.
4
[Cytogenetic effect of low-level 60Co gamma-irradiation of cultured human lymphocytes in the G1 phase of the mitotic cycle].
Radiobiologiia. 1987 Jul-Aug;27(4):479-81.
5
[Use of the sister chromatid differential staining method for studying the lymphocyte proliferative activity of human peripheral blood in normal culture and after in vitro gamma irradiation].[应用姐妹染色单体差异染色法研究正常人外周血淋巴细胞在正常培养及体外γ射线照射后的增殖活性]
Radiobiologiia. 1980 Nov-Dec;20(6):871-6.
6
[Human lymphocyte chromosome reaction to single and fractionated gamma irradiation at different stages of the mitotic cycle].
Radiobiologiia. 1980 May-Jun;20(3):361-7.
7
Evaluation of the premature chromosome condensation scoring protocol after proton and X-ray irradiation of human peripheral blood lymphocytes at high doses range.高剂量范围内质子和X射线照射人外周血淋巴细胞后早熟染色体凝聚评分方案的评估。
Int J Radiat Biol. 2018 Nov;94(11):996-1005. doi: 10.1080/09553002.2018.1490038. Epub 2018 Oct 8.
8
[Frequency of chromosome aberrations induced in human peripheral lymphocytes by in vitro 60Co gamma quanta at doses of 1 to 5 Gr. in an analysis of the 1st-division cells at different fixation times].
Genetika. 1981;17(6):1117-25.
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[Elimination of radiation-induced chromosome damage in a culture of human peripheral blood lymphocytes. II. The frequency of aberrations in the 1st to 5th postradiation mitoses].[人外周血淋巴细胞培养中辐射诱导染色体损伤的消除。II. 辐射后第1至第5次有丝分裂中畸变的频率]
Tsitologiia. 1982 Nov;24(11):1346-50.
10
[Effect of the time before fixation on the yield of chromosome aberrations in a culture of human lymphocytes exposed to gamma rays at different stages of the mitotic cycle].
Radiobiologiia. 1983 Jul-Aug;23(4):471-5.

引用本文的文献

1
Sister chromatid differentiation and isolabeling of chromosomes.姐妹染色单体分化与染色体的同标法
Hum Genet. 1981;56(3):305-8. doi: 10.1007/BF00274684.
2
Chromosomal isolabelling caused by three rounds of synthesis in late replicating regions.在晚期复制区域中三轮合成导致的染色体分离标记
Chromosoma. 1978 Nov 22;69(2):179-83. doi: 10.1007/BF00329916.

本文引用的文献

1
Effect of colchicine on the utilization of labelled thymidine during chromosomal reproduction.秋水仙碱对染色体复制过程中标记胸腺嘧啶核苷利用的影响。
Nature. 1958 Aug 23;182(4634):506-8. doi: 10.1038/182506a0.
2
Effects of treatment on differential staining of BrdU labeled metaphase chromosomes: three-way differentiation of M3 chromosomes.治疗对BrdU标记中期染色体差异染色的影响：M3染色体的三向分化
Chromosoma. 1976 Mar 31;55(1):1-11. doi: 10.1007/BF00288322.
3
A model for compartmentation of de novo and salvage thymidine nucleotide pools in mammalian cells.
哺乳动物细胞中从头合成和补救途径胸苷核苷酸池的区室化模型。
Proc Natl Acad Sci U S A. 1975 Sep;72(9):3333-6. doi: 10.1073/pnas.72.9.3333.
4
Isolabelling is a radiation-induced phenomenon.同位素标记是一种辐射诱导现象。
Chromosoma. 1977 Aug 18;63(1):11-20. doi: 10.1007/BF00292938.