Wolff S, Bodycote J, Rodin B
Chromosoma. 1978 Nov 22;69(2):179-83. doi: 10.1007/BF00329916.
Isolabelling only occurs in CHO cells that have been allowed to replicate for more than 2 but less than 3 cell divisions in the presence of BrdU. The isolabelling is confined to late replicating regions of the chromosomes. The staining patterns obtained indicate that BrdU was incorporated three times in these regions and that the isolabelling did not come from the segregation of label in polynemic chromosomes.
异染色标记仅发生在已在溴脱氧尿苷（BrdU）存在下复制超过2次但少于3次细胞分裂的中国仓鼠卵巢（CHO）细胞中。异染色标记局限于染色体的晚复制区域。所获得的染色模式表明，BrdU在这些区域被掺入了三次，并且异染色标记并非来自多线染色体中标记的分离。
