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80例常见心房扑动的射频导管消融术

Radiofrequency catheter ablation of common atrial flutter in 80 patients.

作者信息

Fischer B, Haissaguerre M, Garrigues S, Poquet F, Gencel L, Clementy J, Marcus F I

机构信息

Centre Hospitalier et Universitaire de Bordeaux, Hôpital Cardiologique du Haut-Lévêque, France.

出版信息

J Am Coll Cardiol. 1995 May;25(6):1365-72. doi: 10.1016/0735-1097(95)00029-4.

Abstract

OBJECTIVES

The purpose of this study was to evaluate the efficacy and safety of radiofrequency catheter ablation of common atrial flutter and to determine the optimal target sites in a large series of patients.

BACKGROUND

Recent studies report the efficacy of radiofrequency current application in the low right atrial region to interrupt and prevent recurrences of common atrial flutter. However, larger groups of patients are required to confirm the efficacy of this technique and to specify the target sites.

METHODS

Two different approaches were used to target the ablation site in 80 consecutive patients. In the first 50 patients, target sites were localized using both anatomic landmarks and electrophysiologic variables. Three anatomic landmarks were used: area 1 = between the tricuspid valve and inferior vena cava orifice; area 2 = between the tricuspid valve and coronary sinus ostium; area 3 = between the inferior vena cava and coronary sinus. The electrophysiologic criterion was to ablate when there was a stable atrial electrogram during the plateau phase. In the next 30 patients we assessed the effect of application of radiofrequency energy in a single line in area 1, 2 or 3 in groups of 10 patients.

RESULTS

Overall atrial flutter was interrupted and rendered noninducible after a single session in 72 patients (90%) and could not be interrupted in 8 (10%). The mean (+/- SD) number of radiofrequency applications was 12 +/- 8. After a mean (+/- SD) follow-up of 20 +/- 8 months, recurrences occurred in 14 patients (17%). The location of the final successful site in the first group of 50 patients was in area 1 in 39%, area 2 in 36% and area 3 in 25%. In the next 30 patients, when lines of radiofrequency lesions were placed at several sites, they produced success rates of 70%, 40% and 10% at areas 1, 2 and 3, respectively.

CONCLUSIONS

Radiofrequency catheter ablation of atrial flutter can be performed with a high success rate and is safe. The highest success rate is achieved with radiofrequency energy applied in the isthmus between the inferior vena cava orifice and tricuspid valve.

摘要

目的

本研究旨在评估射频导管消融治疗常见心房扑动的疗效和安全性,并确定大量患者中的最佳靶点。

背景

近期研究报道了在右心房低位区域应用射频电流来中断和预防常见心房扑动复发的疗效。然而,需要更大规模的患者群体来证实该技术的疗效并明确靶点。

方法

对80例连续患者采用两种不同方法来确定消融部位。在前50例患者中,利用解剖标志和电生理变量来定位靶点。使用了三个解剖标志:区域1 = 位于三尖瓣与下腔静脉口之间;区域2 = 位于三尖瓣与冠状窦口之间;区域3 = 位于下腔静脉与冠状窦之间。电生理标准是在平台期出现稳定心房电图时进行消融。在接下来的30例患者中,我们将10例患者分为一组,评估在区域1、2或3中单行应用射频能量的效果。

结果

72例患者(90%)单次手术后总体心房扑动被中断且不能被诱发,8例(10%)未被中断。射频应用的平均(±标准差)次数为12±8次。平均(±标准差)随访20±8个月后,14例患者(17%)复发。在第一组50例患者中,最终成功部位位于区域1的占39%,区域2的占36%,区域3的占25%。在接下来的30例患者中,当在多个部位放置射频损伤线时,在区域1、2和3的成功率分别为70%﹑40%和10%。

结论

射频导管消融心房扑动成功率高且安全。在下腔静脉口与三尖瓣之间的峡部应用射频能量成功率最高。

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