Uehara F, Ohba N, Sameshima M, Unoki K, Okubo A, Yanagita T, Sugata M, Iwakiri N, Nakagawa S
Department of Ophthalmology, Kagoshima University Faculty of Medicine, Japan.
Jpn J Ophthalmol. 1994;38(4):360-3.
The binding of amaranthin, specific for the Gal beta 1,3 GalNAc and NeuAc alpha 2,3 Gal beta 1,3 GalNAc sequences, to the photoreceptors of the monkey retina was investigated using the avidin-biotinylated peroxidase method. Amaranthin bound to the surfaces of both cone and rod photoreceptors. This and previous lectin histochemical studies show that O-glycoside-linked glycoconjugates are present on the surfaces of both cones and rods: Gal beta 1,3 GalNAc and NeuAc alpha 2,3 Gal beta 1,3 GalNAc are the terminal sugars of the glycoconjugates around cones and rods, respectively.
使用抗生物素蛋白-生物素化过氧化物酶法，研究了对Galβ1,3GalNAc和NeuAcα2,3Galβ1,3GalNAc序列具有特异性的苋菜红与猴视网膜光感受器的结合情况。苋菜红与视锥和视杆光感受器的表面均有结合。这项研究以及之前的凝集素组织化学研究表明，O-糖苷连接的糖缀合物存在于视锥和视杆的表面：Galβ1,3GalNAc和NeuAcα2,3Galβ1,3GalNAc分别是视锥和视杆周围糖缀合物的末端糖。
