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[Use of continuous stacking hybridization in sequencing using modified oligonucleotide matrices].

作者信息

Lysov Iu N, Chernyĭ A A, Balaev A A, Gnuchev F N, Beattie K L, Mirzabekov A D

出版信息

Mol Biol (Mosk). 1995 Jan-Feb;29(1):104-13.

PMID:7723751
Abstract

The opportunity of DNA sequencing by hybridization with oligonucleotide matrix (SHOM) with simultaneously use continuous stacking hybridization and gapped-matrices is considered. The analysis of reconstruction efficiency for various combinations matrices and l-oligonucleotides libraries were made. In most cases combine use of continuous stacking hybridization and gapped matrices permits to decrease the number of additional stacking hybridization twice without lost of efficiency.

摘要

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