先天性中胚层肾瘤伴羊水过多和高钙血症：病例报告及新评估
Polyhydramnios and hypercalcemia associated with congenital mesoblastic nephroma: case report and a new appraisal.
作者信息
Fung T Y, Fung Y M, Ng P C, Yeung C K, Chang M Z
机构信息
Department of Obstetrics and Gynecology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
出版信息
Obstet Gynecol. 1995 May;85(5 Pt 2):815-7. doi: 10.1016/0029-7844(94)00290-t.
BACKGROUND
Polyhydramnios and hypercalcemia are known complications of congenital mesoblastic nephroma. Hypercalcemia has been shown to cause polyuria. Polyuria is believed to be the probable cause for the polyhydramnios, but the exact mechanism remains unknown. To our knowledge, this is the first reported case of a relationship between hypercalcemia and polyhydramnios.
CASE
A 26-year-old primigravida was diagnosed with congenital mesoblastic nephroma and polyhydramnios at 36 weeks' gestation. Neonatal hypercalcemia was detected immediately after delivery at 40 weeks' gestation. After removal of the nephroma, the calcium level normalized.
CONCLUSION
Hypercalcemia may be the mechanism underlying polyhydramnios in cases of congenital mesoblastic nephroma. Calcium levels should be monitored after delivery, and prompt surgical removal of the tumor should be performed.
背景
羊水过多和高钙血症是先天性中胚层肾瘤已知的并发症。高钙血症已被证明会导致多尿。多尿被认为是羊水过多的可能原因，但确切机制仍不清楚。据我们所知，这是首次报道的高钙血症与羊水过多之间关系的病例。
病例
一名26岁初产妇在妊娠36周时被诊断为先天性中胚层肾瘤和羊水过多。在妊娠40周分娩后立即检测到新生儿高钙血症。肾瘤切除后，钙水平恢复正常。
结论
高钙血症可能是先天性中胚层肾瘤病例中羊水过多的潜在机制。产后应监测钙水平，并应及时进行肿瘤的手术切除。
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