Samon L M, Ash K M, Murdison K A
Department of Pediatrics, University of Ottawa School of Medicine, Ontario, Canada.
Obstet Gynecol. 1995 May;85(5 Pt 2):863-5. doi: 10.1016/0029-7844(94)00362-h.
Idiopathic arterial calcification of infancy represents a clinical spectrum involving calcification of large and medium-sized blood vessels with an unknown etiology. Its complications include severe systemic hypertension and cardiomyopathy.
A twin infant with a variant of idiopathic arterial calcification was diagnosed antenatally by the detection of hyperechogenicity of the proximal aorta and central pulmonary vessels. The calcification was apparently isolated to these vessels and was associated with polyhydramnios and hypertrophic cardiomyopathy.
Because antenatal diagnosis is possible, we suggest that there should be a high index of suspicion for idiopathic arterial calcification when there is sonographic hyperechogenicity of vessel walls, evidence of polyhydramnios, cardiomyopathy, or a family history of idiopathic arterial calcification.
婴儿特发性动脉钙化是一种临床综合征，涉及大中型血管钙化，病因不明。其并发症包括严重的系统性高血压和心肌病。
一名患有特发性动脉钙化变异型的双胎儿在产前通过检测主动脉近端和中央肺血管的高回声性得以诊断。钙化显然仅局限于这些血管，并伴有羊水过多和肥厚型心肌病。
由于产前诊断是可行的，我们建议，当存在血管壁超声高回声性、羊水过多、心肌病证据或特发性动脉钙化家族史时，应高度怀疑特发性动脉钙化。
